Monstrous Myostatin Misfortunes – A Collection of Myostatin Deficiency Pictures
July 14, 2007 | by John | Filed Under Animals, People, Science | 93 Comments
Many of you have seen or heard about Wendy the whippet – a dog with a rare genetic mutation that has led to her being called the Arnold Schwarzenegger of dogs.
The genetic mutation is a deficiency in myostatin, which is a growth factor that limits muscle tissue growth.
But that rare genetic defect does not occur only in the whippet breed. In fact, it can and has occurred in other animals… even in humans themselves!
Behold! The ultimate collection of myostatin deficient monstrosities!
Recently part of a genetics study done in the U.S. on mutation in the myostatin gene in whippets, people mistake her for a pitbull with a pinhead.
The uber-muscled whippets are called “bullies,” not because of their nature — Wendy likes nothing better than a good back scratch and isn’t shy about sitting in your lap to ask for one — but because of their size.
She’s about twice the weight of an average whippet, but with the same height and small narrow head — and the same size heart and lungs, which means she probably won’t live as long as normal whippets.
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A heavily-bred breed that produces extraordinary amounts of meat.
Critics call Belgian blues “monster cows” and some countries have advocated eliminating the strain.
Belgian blue cattle have a natural mutation of the gene that codes for myostatin, a protein that counteracts muscle growth.
This mutation also interferes with fat deposition, resulting in very lean meat.
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Muscle in a myostatin-deficient mouse; left, facial muscles, right, forelimb. Top is a normal mouse, bottom is a mouse expressing the mutant phenotype.
Scientists are able to delete the myostatin gene in mice. This is the result.
A muscle ‘explosion’ follows myostatin ‘neutralization’. The control mouse (normal) is shown for comparison. The ActRIIB mice have a genetic defect that prevents myostatin from binding to its purported receptor. Follistatin mice are genetically modified to express high levels of follistatin; this also results failure of myostatin to bind to its receptor. The result in both cases is dramatically enhanced muscle mass. Similar studies indicate large reductions in body fat. Strength and caloric output also increase markedly.
________________________________________
Meet the German baby Superman.
Before he was 5 years old, he could hold 7 lbs. weights with arms extended, something many adults cannot do. He has muscles twice the size of other kids his age and half their body fat.
He was born to a somewhat muscular mother, a 24-year-old former professional sprinter. Her brother and three other close male relatives all were unusually strong, with one of them a construction worker able to unload heavy curbstones by hand.
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A 21 month old toddler from Michigan with myostatin deficiency, he has 40 percent more muscle mass than normal, jaw-dropping strength, breathtaking quickness, a speedy metabolism and almost no body fat. Liam came into the world with many birth defects. He had a small hole in his heart, enlarged kidneys, frequently vomited and was born four weeks premature. Medical records indicated that his biological father was “unusually strong.”
“He could do the iron cross when he was 5 months old,” said his adoptive mother, Dana Hoekstra of Roosevelt Park. She was referring to a difficult gymnastics move in which a male athlete suspends himself by his arms between two hanging rings, forming the shape of a cross.
Two days after birth, he was able to fully stand-up and support his own weight. Months later, he began developing ripped abs, naturally doing pull-ups, inverted sit-ups, Olympic styled iron crosses, thigh muscles compared to that of Lance Armstrong and even punching holes into walls during tantrums (he accidentally gave his Mom a black eye once as well).
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An American illustrator whose body doesn’t produce myostatin.
However, the wonders of science and hard work can surpass even those born with a myostatin deficiency.
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Also known as Little Hercules, is renowned for his physique at an extremely young age. He started training at two years of age and by the time he was six was pressing 4 times more than his own weight. His father only allowed him to eat according to a strict diet, consisting of liquid nutrients and vegetables.
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And then of course, there is former Mr. Olympia Ronnie Coleman and other bodybuilders who can develop physiques such as this:
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One famous bodybuilder who allegedly has a myostatin deficiency was Kenneth “Flex” Wheeler, whose 2nd place finish in the 1999 Mr. Olympia competition can be seen in this video:
Unfortunately, Flex Wheeler’s career was cut short in 2000 after he suffered kidney failure and had to retire from professional body building.
________________________________________
But the real question is, what happens when someone with an even greater myostatin deficiency begins lifting weights, training properly and eating right?
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93 Responses to “Monstrous Myostatin Misfortunes – A Collection of Myostatin Deficiency Pictures”
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[...] [link][more] [...]
Where did that last photograph come from?
The last picture is an utter photoshop and shouldnt be in this post.
How does the last man live? I can’t imagine.
[...] it so happens that such a deficiency makes a lot of living things so terrifyingly beautiful. Here’s a fine gallery. Share This Post:These icons link to social bookmarking sites where readers can share and discover [...]
The first comment by mange is an utter photoshop and shouldnt be in this comment thread.
[...] This article has a number of pics of animals and people (including kids!) with this condition. Monstrous Myostatin Misfortunes – A Collection of Myostatin Deficiency Pictures [...]
Oh jesus christ, that last picture makes me want to throw up.
[...] The ultimate collection of myostatin deficient monstrosities. [link] [...]
“But the real question is, what happens when someone with an even greater myostatin deficiency begins lifting weights, training properly and eating right?”
You don’t make any sense, in the embedded video you show a professional muscle-trainer with this syndrome, and he is not as big as the man made Coleman…
But the real question is, what happens when someone with an even greater myostatin deficiency begins lifting weights, training properly and eating right?
That’s Hot!
ya wtf.. the last one is photoshop and has been around the web for ages. nobody can be this built/ugly
Actually flex wheeler probably has no deficiency but was taking massive amounts of steroids, growth hormone, insulin, IGF-1. How do you think he ended up with kidney failure. And although Ronnie Coleman works his ass off, he’s far from natural himself.
[...] Monstrous Myostatin Misfortunes – A Collection of Myostatin Deficiency Pictures – a miostatina é uma proteÃna que impede o crescimento muscular. Quem produz mais, tem mais dificuldade em desenvolver músculos, quem tem menos, mais facilidade. Acontece que uma mutação genética pode fazer com que um indivÃduo não produza nada, possibilitando um crescimento muscular teoricamente ilimitado, é o caso de Wendy, a cadela da foto. Nada bonito, mesmo com os olhos de quem não oferece muito perigo. Mas espera que piora. O remédio Myostat interfere na produção da proteÃna e promete não só crescimento muscular mas também criação de novas fibras musculares, o paciente bomba. Tudo para ficar mais ou menos assim ou gatÃssima assim. [...]
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[...] there’s crazy post on who-sucks dot com titled monstrous myostatin misfortunes with equally crazy pics of some mighty massive muscle magnification caused by myostatin deficiency. [...]
is the last picture for real??!! whoaaa!!
Damn the last picture… the guy’s a freak. Looks like he even develloped muscles on his balls lol.
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The dog looks like something out of Resident Evil!
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Wait did the scientist do that to the mice!? If they did, imagine if the government told them to do it to humans!
The last photo is a photo-morph. The others are not.
I don’t know why Ronnie Coleman is featured in this story, since he obtained his physique through hard work and lots and lots of steroids. The other mammals in this story don’t need steroids to look that way.
Кошмар Ñ?амый наÑ?тоÑ?щий !
I hope you’re not serious about the Tom Fleming entry. Tom is a friend of mine and works hard to stay in shape. He is not myostatin deficient. It looks like the writer found a blog entry from Jeff Parker’s Parkerspace.com blog several years ago. In it Parker jokes about his friend Tom’s physique. It’s obvious to anyone reading the entry that he is poking fun at Tom. It’s amazing to me this stuff will get posted with no real effort to research or fact-check sources.
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[...] mware I found some interesting info on the myostatin deficiency. Monstrous Myostatin Misfortunes – A Collection of Myostatin Deficiency PicturesMany of you have seen or heard about Wendy the whippet – a dog with a rare genetic mutation that has [...]
Can these guys have normal sex? Are their sexual organs shrunken, or are they gargantuan! We haven’t heard any information on this. Just what does something like this do to a guy’s penis? Or how does it affect his sexuality? Is it even possible to have simple intercourse with someone like this? Is this a freakshow, or can these guys really perform and really procreate? This is a mighty strange story…
Ass Licking Videos…
Sorry, it just sounds like a crazy idea for me
…
We’re actually building a complete site devoted to buff animals over at http://buffanimals.com which was of course inspired by wendy. Naturally Myostatin deficient animals will be the main focus. Get over there and have a look if you can and if you have any news or pics that would be fantastic.
P.
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You should check out the phsyiological differences in Einstien’s brain. It was actually slighty smaller than average but had a mutation… learned about it in pysch’ class. A side note, you have to feed them, just like a racecar will burn quite a bit of gas. Superior but somehow not in common practice.
[...] Monstrous Myostatin Misfortunes – A Collection of Myostatin Deficiency Pictures [...]
ian-
einsteins brain was missing the parietal operculum region and the lateral sulcus, which have to deal with language and speech mostly. he also had more glial cells to neurons,
as for “burning a bit of gas”, its possible but not really documented for myostatin deficients i think. you might be thinking about the other genetic abnormality, PEPCK-C.
cmon people
above the last picture says:
“But the real question is, what happens when someone with an even greater myostatin deficiency begins lifting weights, training properly and eating right?”
so its asking a question and showing a picture(photoshoped) of a possible person with the genetic anormality, bodybuilds and eats right.
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Damn the last picture… Photoshop
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The last image is not real you retards.
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There certainly could be a place in the world to feed people meat that is leaner (Belgian Blue cow) but one would think that the human bone structure could not support too much muscle mass over longer periods of time.
I thin I’ll just lift weights and eat right.
Very good
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IS THERE ANY OTHER PHOTOS OR INFO ON THE GUY IN THE LAST PHOTO?
The last guy is a fabricated photo. As far as myostatin inhibition goes, bring it on. If there was money in it the pharmaceutical companies would be all over it. If it got a Senator hard, they’d be all over it. People are afraid of muscle and don’t understand it so they fear it. Myostatin would not have the side effects of steroids or the hostility bull with it so lets get big. I’m 43 and I’d do it tomorrow. I understand I’d have to get in shape first because the load on the heart gaining that fast would be significant.
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If the last guy is photoshopped where’s the original image? & who is he?
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I wish this gene can inject into my blood.
Wanna know how I can become later after 2 years
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Myostatin inhibitors again! Seems like I’ve been reading about this stuff for years! I just came across something called myoT12. Anybody know anything about Peak Wellness BioPharma? 46% reductions in myostatin is nothing to sneeze at, right? I don’t know, it looks promising. i found it at prosource.net. would LOVE to hear if someone tried it yet.
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I heard of myo T12 but dont know, sounds awsome if it works some supplements do work but are rare. Blue Belgans have smaller than normal bone but are stronger. There known for good milk and meat production some of the best in the industry. People have been reported to have lived without myostatin like the young romanian guy, and others in the past. Some pharmacutical co. have worked on a vaccine that shuts off the myostatin but its all research right now it has been shown to work in animals, human trials are possible. It is very well possible Flex Wheeler and Ronnie Coleman both have one gene on one off. A michigan man who also was a cop could do hand stand push ups after walking on his hands to the end of a diving board while weighing 300 plus pounds. He didnt lift weights but was just really strong he could also run abnormaly fast for a large guy. The last photo is awsome I would also like to get in on a myostatin blocking vaccine. With the advances in science and technology and some money it is possible we could have this done in our life time.
My son is 3 yrs old and has the myostatin gene. He does pull ups, one arm push ups, lifts my furniture, his 12 yr. old brother that weighs 70 lbs., and picks up his dad’s 40 lbs. weights with one hand like its nothing! its amazing! Do have side affects though – shortness and can cause heart problems
You have a mistake in one of your photos. The first mouse photo (big mouse on left and small mouse on right) is not in fact the myostatin mutant mouse. It is likely a mouse carrying a mutation for the protein leptin or its’ receptor.
Liam does not have a Myostatin Deficiency his body produces normal levels of Myostatin and therefore he should not be on this page.
that mouse looks so funny! lol tjat is crazy
very strange from humans to animals the head remains the same size despite the size of the body!!! this man must be eating like a beast! or ’steroids’ like food and food like steroids!!!
[...] Link ?????? ??? ?????? [...]
Very good thanks
Riiiight.
I am not going to call total b.s. on the myostatin thing.
However I will say that with the people who have unnatural strength, agility and similar physical prowess there is possibly quite a bit more going on in there genetics than just simple lack of or low myostatin expression.
And if they could fins a way to mimic the total genetic/chemical composition in those people via chemicals and supplements then it would have great potential.
This is a bit wired, they are so different, anyway I like this article, haven’t read one like this. Rosetta Stone French and Rosetta Stone Chinese
That muscle dog is worth a lot of money to people that cruelly fight dogs. Hope he’s kept under lock and key.
That last picture has got to be Photoshop. That poor man, if it isn’t.
The last photo is fake. You’re an idiot if you think that photo is real. It’s photoshopped.
A tank has appeared ._.
PEELS HERE.
the last photo is surely fake because i know almost all the body builders because to see at body building salons and no one is like him
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I am not going to call total b.s. on the myostatin thing.
However I will say that with the people who have unnatural strength, agility and similar physical prowess there is possibly quite a bit more going on in there genetics than just simple lack of or low myostatin expression.
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